Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WRN Q14191 WRN RecQ like helicase Enzyme 2.6E-34 0.524 0.808
USHBP1 Q8N6Y0 USH1 protein network component harmonin binding protein 1 3.0E-17 0.705 0.269
TUBA1C Q9BQE3 tubulin alpha 1c Cellular structure 7.4E-03 0.663 0.577
TTC28 Q96AY4 tetratricopeptide repeat domain 28 Receptor 1.00 0.760 0.308
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
RNF43 Q68DV7 ring finger protein 43 0.73 0.584 0.577
RALY Q9UKM9 RALY heterogeneous nuclear ribonucleoprotein 0.14 0.656 0.385
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
PVT1 Pvt1 oncogene 0.495 0.731
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
OPCML Q14982 opioid binding protein/cell adhesion molecule like 0.23 0.606 0.654
NEK10 Q6ZWH5 NIMA related kinase 10 Kinase 7.7E-10 0.705 0.269
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
MTX1 Q13505 metaxin 1 1.3E-02 0.546 0.731
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808